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@CSE_CurrentAffairs
Channel's geo and language: India, English
Category: Education

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10 Mar 2023, 09:58

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Forward from: UPSC Prelims Mains Current
Join Our DELHI INSTITUTE FOR FOR CIVIL SERVICES (DICS) UPSC Exclusive Youtube Channel.

Features of our channel

- Videos of Weekly Current Affairs (Live)
- Rapid Revision Videos
- The Hindu Science and Tech page analysis
- Lectures related to NCERT
- Test Series Analysis and Explanation (Live)
- Gyan Ke Moti series

Also other information related to UPSC will be posted.

So subscribe to DICS UPSC Channel Today.

Channel Link:- https://youtube.com/@delhiinstituteforcivilservices
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10 Mar 2023, 06:56

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🔆Chimeric Antigen Receptor (CAR)-T Cell T Therapy

✅ Why in News: the researchers have said that India’s first indigenously developed Chimeric Antigen Receptor (CAR)-T Cell T therapy for specific types of cancer patients has shown promising results and could be the safest therapy in this category so far.

▪️What is CAR-T cell therapy?

✅CAR-T cells are a patient’s own immune cells that are genetically engineered in the laboratory to fight cancer.
✅CAR-T cell is a prospective therapy that has ushered in a new era of curing refractory and stubborn cancers.
✅CAR T cell therapy is used as third or second-line treatment for patients of specific types of cancers of blood and lymph nodes. In India, those willing to undergo this treatment have to travel to other countries, mostly the US.
✅T-cell receptor is widely used in developed nations for immunotherapy during cancer treatment.
✅However, the technology was not available in India yet.

▪️How does it work?

✅The therapy targets leukaemia and lymphoma.
✅Leukaemia is cancer of blood-forming tissues, including bone marrow.
✅Lymphoma is a cancer of the lymphatic system, which is part of the body's germ-fighting network.
✅It uses lentiviral technology.
✅In gene therapy, this is a method of inserting, modifying, or deleting genes in organisms using lentivirus, a family of viruses responsible for diseases such as AIDS (acquired immunodeficiency syndrome).
✅As part of the treatment, a specific type of white blood cells called T cells are changed in the lab so they can find and destroy cancer cells.
✅It is also sometimes referred to as a type of cell-based gene therapy because it involves altering genes inside T cells to help them attack cancerous cells.

▪️Significance

✅HCAR19 therapy : The participants received autologous HCAR19 therapy (humanised CAR 19 therapy developed by IIT Bombay and it was observed that there were no dose-limiting toxicities and only low grade Cytokine Release Syndrome (CRS) was seen in 40 percent of participants.
✅No neurotoxicity syndrome : None of the participants had immune effector cell-associated neurotoxicity syndrome.
✅Safer version : Overall, the novel humanised HCAR19 tested in phase one clinical trials for adult lymphoma was found to be safe and has shown promising early signs of activity.
✅No deaths : Post-CAR-T cell therapy none of the participants required ICU admission and there were no CAR-T treatment related deaths.

▪️Therapy in India/ Way forward

✅Two start-ups : ImmunoACT along with Immuneel Therapeutics are two startups currently working to make CAR T cell therapy available in India.
✅Low cost therapy : Both of these companies have said the therapy would be available in the country at a fraction of cost charged for the treatment in the developed countries like the US where it can cost about Rs 2-3 crore.

Source HT


#Biotechnology
IIT-B-Tata hosp cancer therapy trials show ‘promising’ results
Mumbai: Nearly 14 months after the clinical trials of the indigenously developed CAR-T technology for blood cancer treatment was kicked off at the Tata Memorial Centre (TMC), researchers have concluded the first phase of trials and called the results “encouraging”
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9 Mar 2023, 17:39

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Forward from: UPSC Prelims Mains Current
प्रिय अभ्यर्थी,

होली पर्व के शुभ अवसर पर संस्कृति IAS आपके लिये लेकर आया है विशेष छूट, ऑफर 1 - 10 मार्च तक उपलब्ध है।

कोर्स में मिलने वाली सुविधाएँ:

1: लाइव
2: ऑनलाइन
3: पेनड्राइव
4: DLP

Visit : www.sanskritiias.com | Call : 9555124124 | 7428085757
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9 Mar 2023, 16:31

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9 Mar 2023, 14:55

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Opportunity Alert.
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9 Mar 2023, 05:26

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9 Mar 2023, 05:26

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#gs2
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8 Mar 2023, 17:04

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Forward from: UPSC Prelims Mains Current
प्रिय अभ्यर्थी,

होली पर्व के शुभ अवसर पर संस्कृति IAS आपके लिये लेकर आया है विशेष छूट, ऑफर 1 - 10 मार्च तक उपलब्ध है।

कोर्स में मिलने वाली सुविधाएँ:

1: लाइव
2: ऑनलाइन
3: पेनड्राइव
4: DLP

Visit : www.sanskritiias.com | Call : 9555124124 | 7428085757
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8 Mar 2023, 02:51

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🔆Rumours of migrant workers being assaulted in Tamil Nadu have triggered concern among manufacturers in the state.

📍What is the legal framework for migrant welfare?

✅The Inter-State Migrant Workmen Act, 1979 looks into the welfare of the labourers.
✅The Act mandates that the establishment which proposes to employ migrant workers be required to be registered with destination states.
✅Contractors will also have to obtain a licence from the concerned authority of the home states as well as the host states.
However, in practice, this Act has not been fully implemented.

📍This Act has been subsumed into the four broad labour codes notified by the Centre:
✅The Code on Wages, 2019;
✅The Industrial Relations Code, 2020;
✅The Code on Social Security, 2020; and
✅The Occupational Safety, Health and Working Conditions Code, 2020.
These have not been implemented yet.
Also, the registration under the inter-state migrant workers’ act is negligible
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7 Mar 2023, 15:34

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Forward from: UPSC Prelims Mains Current
प्रिय अभ्यर्थी,

होली पर्व के शुभ अवसर पर संस्कृति IAS आपके लिये लेकर आया है विशेष छूट, ऑफर 1 - 10 मार्च तक उपलब्ध है।

कोर्स में मिलने वाली सुविधाएँ:

1: लाइव
2: ऑनलाइन
3: पेनड्राइव
4: DLP

Visit : www.sanskritiias.com | Call : 9555124124 | 7428085757
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7 Mar 2023, 13:51

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Forward from: UPSC Prelims Mains Current
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7 Mar 2023, 05:58

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🔆China increases defence spending by 27%

#gs2
#ir
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7 Mar 2023, 05:58

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🔆Ayurvedic practice

#gs2
#health
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6 Mar 2023, 17:57

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Forward from: UPSC Prelims Mains Current
प्रिय अभ्यर्थी,

होली पर्व के शुभ अवसर पर संस्कृति IAS आपके लिये लेकर आया है विशेष छूट, ऑफर 1 - 10 मार्च तक उपलब्ध है।

कोर्स में मिलने वाली सुविधाएँ:

1: लाइव
2: ऑनलाइन
3: पेनड्राइव
4: DLP

Visit : www.sanskritiias.com | Call : 9555124124 | 7428085757
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6 Mar 2023, 16:50

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Forward from: UPSC Prelims Mains Current
Registration link: https://forms.gle/SzRvfuYjPjp4SqhS6

Call +917397767226 to register for the Mock Board on 11th March 2023 (Saturday) in Chennai.


Best wishes!
Officers IAS Academy.
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6 Mar 2023, 05:26

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🔆G20 countries failed to find a middle path in Ukraine issue

#gs2
#ir
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6 Mar 2023, 05:26

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🔆Why independence of election watchdog is important?

#gs2
#polity
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5 Mar 2023, 15:37

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Forward from: UPSC Prelims Mains Current
प्रिय अभ्यर्थी,

होली पर्व के शुभ अवसर पर संस्कृति IAS आपके लिये लेकर आया है विशेष छूट, ऑफर 1 - 10 मार्च तक उपलब्ध है।

कोर्स में मिलने वाली सुविधाएँ:

1: लाइव
2: ऑनलाइन
3: पेनड्राइव
4: DLP

Visit : www.sanskritiias.com | Call : 9555124124 | 7428085757
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5 Mar 2023, 04:51

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🔆National Youth Parliament Festival (NYPF)

✅Shri Om Birla, Speaker Lok Sabha to address the valedictory function of the 4th National Youth Parliament Festival on March 2, 2023.

♻️About NYPF :

✅The objective of the National Youth Parliament Festival is to hear the voice of the youth who will join various careers in the near future, including public services.

✅The first edition of NYPF was held in 2019 with the theme, “Be the voice of New India and find solutions and contribute to policy”.

✅The second edition was held in 2021  and the third edition in 2022.

✅The fourth edition was launched with the theme, “Ideas for a better tomorrow : India for the World”.

✅District Youth Parliaments (DYP) were conducted from 25-29 January 2023.

✅More than 2.01 lakh youth from 748 districts of all the states and UTs participated at 150 venues across the country.

✅The first and second position holders of DYP participated in the State Youth Parliament (SYP) Festival.

✅The first three winners will get the opportunity to speak before the speaker of the  Lok Sabha on March 2, 2023.


#⃣Tag:   #GS2 #Policies #Youth #Parliamemt #Pre
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4 Mar 2023, 18:44

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Forward from: UPSC Prelims Mains Current
प्रिय अभ्यर्थी,

होली पर्व के शुभ अवसर पर संस्कृति IAS आपके लिये लेकर आया है विशेष छूट, ऑफर 1 - 10 मार्च तक उपलब्ध है।

कोर्स में मिलने वाली सुविधाएँ:

1: लाइव
2: ऑनलाइन
3: पेनड्राइव
4: DLP

Visit : www.sanskritiias.com | Call : 9555124124 | 7428085757
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